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Industry News for Integrative Therapeutics

825 Challenger Drive
Green Bay, Wisconsin 54311

    PepZinGI Zinc-Carnosine Clinically Proven for Gastrointestinal Mucosal Health

    According to the National Digestive Diseases Information Clearinghouse (NDDIC), approximately 60-70 million Americans suffer from some form of digestive distress. With such a large subset of the population requiring gastrointestinal support, healthcare practitioners need to rely on solutions that have been proven to provide endoscopic improvement.

    Clinical-studies demonstrating the benefits Zinc-Carnosine suggest that supplementation with this ingredient should be considered when creating a gastrointestinal protocol. PepZinGI® brand Zinc-Carnosine has been successfully used in Japan since the early 1990s to support mucosal integrity, gastrointestinal immune defense, and occasional indigestion. This unique ingredient combines L-carnosine, a naturally occurring dipeptide with elemental zinc for antioxidant and mucosal tissue support.*

    The makers of clinically-studied PepZinGI® have chosen to partner with Integrative Therapeutics™, the gastrointestinal leader in the dietary supplement industry, to introduce a stand-alone Zinc-Carnosine.

    “Zinc-Carnosine is the perfect addition to our Six Principles for Restoring Gastrointestinal Health approach to helping practitioners create customized gastrointestinal protocols,” explains Jeremy Appleton, ND, the Director of Scientific Affairs for Integrative Therapeutics, “We chose to use the clinically-validated PepzinGI® brand because providing truly evidence-based medicine is our first consideration in formulating new products.” 

    Zinc-Carnosine is unique in that it supports the natural cytoprotective mechanisms without interfering in the normal digestive process (i.e., unlike most digestive aids, it does not suppress stomach acid production or neutralize HCl, which is required for mineral absorption).*

    “The efficacy and safety of PepZinGI brand Zinc-Carnosine have been demonstrated in humans in numerous published double-blind and open-label clinical trials,” explains Appleton, “Most successful clinical trials of Zinc-Carnosine used 37.5 to 75 mg twice daily for 8 weeks. This amount of Zinc-Carnosine provides 7.5 mg to 15 mg of elemental zinc per dose.”

    For dosing information and product details on Integrative Therapeutics’ Zinc-Carnosine, visit



    About Integrative Therapeutics

    Integrative Therapeutics, LLC manufactures and distributes proprietary, natural supplements exclusively to medical professionals. Our manufacturing facility meets stringent quality standards and is an organically certified and drug GMP audited facility. Find out more at


    *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



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